Lars Farde Selected Research

2- (6- (methylamino)pyridin- 3- yl)- 1,3- benzothiazol- 6- ol

1/2024	High Contrast PET Imaging of Subcortical and Allocortical Amyloid-β in Early Alzheimer's Disease Using [11C]AZD2184.
9/2015	β-Amyloid binding in elderly subjects with declining or stable episodic memory function measured with PET and [¹¹C]AZD2184.
4/2013	Low background and high contrast PET imaging of amyloid-β with [11C]AZD2995 and [11C]AZD2184 in Alzheimer's disease patients.
11/2009	Detection of amyloid in Alzheimer's disease with positron emission tomography using [11C]AZD2184.
3/2009	AZD2184: a radioligand for sensitive detection of beta-amyloid deposits.

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Lars Farde Research Topics

Disease

25	Schizophrenia (Dementia Praecox) 01/2023 - 01/2002
14	Alzheimer Disease (Alzheimer's Disease) 01/2024 - 06/2006
12	Parkinson Disease (Parkinson's Disease) 01/2020 - 10/2004
11	Mental Disorders (Mental Disorder) 01/2018 - 03/2002
6	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2023 - 04/2008
6	Psychotic Disorders (Schizoaffective Disorder) 01/2023 - 01/2019
6	Amyloid Plaque 12/2015 - 06/2006
5	Major Depressive Disorder (Major Depressive Disorders) 01/2019 - 11/2011
4	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 09/2009 - 02/2005
3	Cognitive Dysfunction 01/2024 - 09/2014
3	Brain Neoplasms (Brain Tumor) 01/2023 - 01/2020
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2023 - 01/2020
2	Gliosis 01/2023 - 12/2015
2	Neoplasm Metastasis (Metastasis) 01/2023 - 01/2021
2	Substance-Related Disorders (Drug Abuse) 01/2023 - 09/2000
2	Neoplasms (Cancer) 12/2021 - 01/2021
2	Neuroinflammatory Diseases 12/2015 - 09/2015
2	Anxiety Disorders (Anxiety Disorder) 02/2014 - 11/2013
2	Juvenile Myoclonic Epilepsy 02/2012 - 06/2005
2	Cerebrovascular Disorders (Cerebrovascular Occlusion) 11/2002 - 08/2002
1	Alcoholism (Alcohol Abuse) 01/2023
1	Synucleinopathies 01/2022
1	Ataxia Telangiectasia (Louis Bar Syndrome) 12/2021
1	Glioblastoma (Glioblastoma Multiforme) 12/2021
1	Nervous System Diseases (Neurological Disorders) 01/2021
1	Autistic Disorder (Autism) 01/2021
1	Epilepsy (Aura) 01/2020
1	Type 2 Diabetes Mellitus (MODY) 12/2018
1	Autism Spectrum Disorder 10/2018
1	Antisocial Personality Disorder (Antisocial Personality) 01/2018
1	Necrosis 04/2017
1	Obesity 02/2016
1	Weight Loss (Weight Reduction) 02/2016
1	Brain Diseases (Brain Disorder) 06/2015
1	Mood Disorders (Mood Disorder) 05/2015

Drug/Important Bio-Agent (IBA)

15	Dopamine (Intropin)FDA LinkGeneric 01/2023 - 05/2002
12	Serotonin (5 Hydroxytryptamine)IBA 01/2022 - 03/2002
9	Antipsychotic Agents (Antipsychotics)IBA 01/2022 - 05/2002
8	Amyloid (Amyloid Fibrils)IBA 01/2024 - 11/2009
7	Dopamine D2 Receptors (Dopamine D2 Receptor)IBA 01/2023 - 01/2002
7	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 01/2019 - 09/2000
6	Biomarkers (Surrogate Marker)IBA 01/2020 - 06/2006
5	2- (6- (methylamino)pyridin- 3- yl)- 1,3- benzothiazol- 6- olIBA 01/2024 - 03/2009
5	FLB 457IBA 09/2021 - 01/2002
4	RacloprideIBA 01/2023 - 02/2005
4	Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA 01/2021 - 01/2003
4	Proteins (Proteins, Gene)FDA Link 01/2019 - 09/2015
4	Dopamine Receptors (Dopamine Receptor)IBA 01/2018 - 05/2002
4	5-HT1B Serotonin ReceptorIBA 01/2016 - 07/2008
4	Amyloid beta-PeptidesIBA 09/2015 - 03/2009
3	Monoamine Oxidase (MAO)IBA 01/2023 - 01/2020
3	osimertinibIBA 01/2023 - 01/2020
2	ErbB Receptors (EGF Receptor)IBA 01/2023 - 01/2020
2	Tyrosine Kinase InhibitorsIBA 01/2023 - 01/2020
2	5-HT1A Serotonin ReceptorIBA 01/2022 - 06/2005
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2022 - 11/2017
2	Metabotropic Glutamate 5 ReceptorIBA 01/2020 - 01/2018
2	LigandsIBA 01/2020 - 12/2015
2	SCH 23390IBA 01/2019 - 05/2002
2	Neurotransmitter Agents (Neurotransmitter)IBA 11/2015 - 12/2014
2	AZD3241IBA 09/2015 - 06/2015
2	Peroxidase (Myeloperoxidase)IBA 09/2015 - 06/2015
2	Quetiapine Fumarate (Seroquel)FDA Link 11/2013 - 11/2011
2	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 08/2013 - 09/2012
2	N- (3- iodoprop- 2- enyl)- 2- beta- carbomethoxy- 3- (4- methylphenyl)nortropaneIBA 02/2012 - 02/2005
2	Clozapine (Clozaril)FDA LinkGeneric 11/2011 - 03/2003
2	vinpocetineIBA 11/2002 - 08/2002
1	EnzymesIBA 01/2023
1	Polytetrafluoroethylene (Teflon)FDA Link 01/2023
1	AZD1390IBA 12/2021
1	Protein Kinases (Protein Kinase)IBA 12/2021
1	AfatinibIBA 01/2021
1	Carbon-11IBA 12/2020
1	Fluorine-18IBA 12/2020
1	Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA 01/2020
1	Dopamine D1 Receptors (Dopamine D1 Receptor)IBA 01/2020
1	fenobamIBA 01/2020
1	AZD9272IBA 01/2020
1	VortioxetineIBA 01/2019
1	Antidepressive Agents (Antidepressants)IBA 01/2019
1	Insulin (Novolin)FDA Link 12/2018
1	Aminobutyrates (Aminobutyric Acid)IBA 10/2018
1	Glutamic Acid (Glutamate)FDA Link 01/2018
1	ApolipoproteinsIBA 11/2017
1	Apolipoproteins E (ApoE)IBA 11/2017
1	Glucose (Dextrose)FDA LinkGeneric 11/2017
1	Tumor Biomarkers (Tumor Markers)IBA 04/2017
1	N- (3- (4- chlorophenyl)- 2- (3- cyanophenyl)- 1- methylpropyl)- 2- methyl- 2- ((5- (trifluoromethyl)pyridin- 2- yl)oxy)propanamideIBA 02/2016
1	RimonabantIBA 02/2016
1	CB1 Cannabinoid Receptor (CB1 Receptor)IBA 02/2016
1	N,N- dimethyl- 7- (4- (2- (pyridin- 2- yl)ethyl)piperazin- 1- yl)benzofuran- 2- carboxamideIBA 01/2016
1	benzofuranIBA 01/2016
1	Peptides (Polypeptides)IBA 12/2015
1	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2015
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 12/2014
1	AutoreceptorsIBA 08/2014

Therapy/Procedure

2	Therapeutics 08/2014 - 04/2013
1	Drug Therapy (Chemotherapy) 01/2022
1	Radiotherapy 12/2021
1	Aftercare (After-Treatment) 09/2015